PCHP

1-(1-Phenylcyclohexyl)-4-hydroxypiperidine (PCHP) is a chemical compound from the arylcyclohexylamine class, which is closely related to phencyclidine (PCP) and its derivatives. PCHP is a metabolite of PCP, meaning it is one of the substances formed when PCP is broken down in the body.

Key Characteristics of PCHP:

1. Chemical Structure: PCHP features a phenyl group attached to a cyclohexyl ring and a hydroxyl group substituted on the piperidine ring, giving it unique properties within its class.
2. Metabolic Role: As a metabolite of PCP, PCHP is produced during the metabolic processing of PCP in the liver, making it significant in pharmacokinetic studies.
3. Pharmacological Relevance: PCHP retains some interaction with NMDA receptors, though its potency and effects are generally reduced compared to PCP.

Research Applications:

PCHP is primarily studied in the context of:

• Pharmacokinetics: Understanding how PCP is metabolized in the body.
• Toxicology: Examining the pathways and effects of PCP derivatives and their metabolites.
• Neuropharmacology: Exploring receptor interactions and dissociative properties within the arylcyclohexylamine family.

Important Information:

PCHP is intended for research purposes only and is not approved for human or veterinary use. Researchers studying PCP and its metabolites may use PCHP in controlled laboratory settings to investigate its properties and role in metabolism.