PD-137889

PD-137889 is a chemical compound classified as an arylcyclohexylamine derivative. This compound is a structural analogue of phencyclidine (PCP), sharing a similar chemical backbone but featuring modifications that distinguish it within the same family. PD-137889 is known to act as a dissociative anesthetic and an NMDA receptor antagonist, making it of interest in pharmacological and neurochemical research.

Key Characteristics of PD-137889:

1. NMDA Receptor Antagonism: PD-137889 blocks NMDA receptors in the central nervous system, which are involved in synaptic plasticity, learning, and memory.
2. Chemical Structure: It is similar to PCP but with structural differences that may alter its potency, binding affinity, and pharmacological profile.
3. Research Significance: PD-137889 is primarily studied for its effects on neural pathways, dissociative mechanisms, and potential therapeutic applications.

Research Applications:

PD-137889 is utilized in:

• Neuropharmacology: Studying the role of NMDA receptors in neural activity and dissociative states.
• Receptor Binding Studies: Exploring how structural analogues of PCP interact with various receptor sites.
• Toxicological Research: Understanding the safety profiles and potential side effects of dissociative anesthetics.

Important Information:

PD-137889 is intended for research purposes only and is not approved for human or veterinary use. It should be handled by qualified professionals in controlled laboratory environments.